Table 2.
Variation of miR-10b level by distinct clinicopathological features analyzed by the t-test with Bonferroni correction.
| Clincopathological features | Cases, N | miR-10b level | t-statistic | P-value |
|---|---|---|---|---|
| Age, years | 0.375 | 0.341 | ||
| <50 | 25 | 2.31 | ||
| ≥50 | 19 | 2.18 | ||
| Tumor diameter, cm | 7.192 | 0.008 | ||
| ≤5 | 27 | 1.56 | ||
| >5 | 17 | 3.44 | ||
| Histological grading | 7.537 | 0.007 | ||
| I + II | 26 | 1.39 | ||
| III | 18 | 3.62 | ||
| Clinical staging | 8.941 | 0.004 | ||
| I + II | 22 | 1.05 | ||
| III | 22 | 3.70 | ||
| Lymph node metastasis | 9.089 | 0.003 | ||
| No | 21 | 0.63 | ||
| Yes | 23 | 3.76 | ||
| Her2 status | 6.210 | 0.012 | ||
| Negative | 28 | 1.33 | ||
| Positive | 16 | 2.94 | ||
| ER status | 3.830 | 0.039 | ||
| Negative | 24 | 2.86 | ||
| Positive | 20 | 1.15 | ||
| PR status | 3.590 | 0.041 | ||
| Negative | 25 | 3.27 | ||
| Positive | 19 | 2.14 | ||
| Pathological subtypes | 0.045 | 0.780 | ||
| Invasive ductal carcinoma | 29 | 2.75 | ||
| Others | 15 | 2.59 | ||
| Ki-67 mitotic index, (%) | 5.391 | 0.022 | ||
| Low (≤14) | 26 | 1.46 | ||
| High (>14) | 18 | 2.91 |