Table 1.
Dose-response effects of ACN on XD-XO conversion, GSH, (O2·−) production and TBARS in rat stomach.
| XO % of total | GSH μmol/mg protein | (O2·−) nmol/mg protein | TBARS nmol/mg protein | |
|---|---|---|---|---|
| Control | 7.09±0.47 | 4.30±0.40 | 4.81±0.33 | 0.99±0.14 |
| ACN (10 mg/kg) | 15.86*±0.76 | 3.53*±0.35 | 22.21*±1.75 | 2.34*±0.27 |
| ACN (25 mg/kg) | 26.03*±1.18 | 2.39*±0.30 | 47.64*±2.96 | 3.36*±0.31 |
| ACN (50 mg/kg) | 36.99*±2.01 | 1.55*±0.27 | 75.62*±4.71 | 4.49*±0.29 |
Animals were sacrificed 2 h after treatment, n=6. Data were presented as mean ±SD.
*
Significantly different from the corresponding control group at p<0.05.