Table 2.
Comparison of selected clinical and biochemical parameters between patients with mild/moderate and advanced fibrosis.
| Parameter | Mild/moderate fibrosis F0–F2 (n=99) | Advanced fibrosis F3–F4 (n=27) | P value |
|---|---|---|---|
| Age (years)* | 43.01±13.43 | 50.89±11.37 | 0.00618 |
| Gender: female/male (%) | 40.4/59.6 | 44.4/55.6 | 0.5666 |
| BMI (kg/m2)* | 27.85±2.51 | 32.6±3.36 | 0.00087 |
| Obesity (%/n) (BMI ≥30 kg/m2) | 11.1/11 | 48.15/13 | 0.0110 |
| Overweight (%/n) (BMI ≥25 and <30kg/m2) | 81.81/70 | 44.44/12 | 0.0013 |
| Diabetes mellitus (%/n) | 11.1/11 | 66.6/18 | 0.0067 |
| ALT (U/L)* | 94.81±60.38 | 104.81±67.71 | 0.45904 |
| AST (U/L)* | 59.41±45.95 | 94.41±54.16 | 0.00099 |
| AST/ALT ratio* | 0.66±0.29 | 1.08±0.46 | 0.000041 |
| Albumin (g/dL)* | 4.34±0.48 | 4.22±0.42 | 0.2537 |
| Platelet count (×109/L)* | 292.51±79.73 | 219.44±69.32 | 0.00003 |
*
Mean ± standard deviation;
ALT – alanine aminotransferase; AST – aspartate aminotransferase; BMI – body mass index; n – number of cases.