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. 2012 Apr 1;18(4):BR149–BR155. doi: 10.12659/MSM.882617

Figure 3.

Figure 3

ERBB2 is a validated target of miR-125b. (A) 3′UTR of ERBB2 is a target of miR-125b predicted by miRBase, TargetScan, miRanda and PicTar. (B) The reporter assay result with each bar representing values from three independent experiments. The transfection efficiency was normalized by co-transfected renilla luciferase and the light units were calculated by relative luciferase activity of firefly to renilla. * P<0.05. (C) Representative image of the protein level of ERBB2. GAPDH was used as a reference control. (D) quantitative analysis of the relative protein levels of ERBB2 normalized to those of GAPDH was shown. Data were mean ±SD of three independent experiments. * P<0.05.