Table 3.
Characteristics of chronic kidney disease in endemic UUC cases
| Chronic kidney disease | Stages 0–2 | Stage 3 | Stage 4 | Stage 5 |
|---|---|---|---|---|
| N (%) | 11 (16.4%) | 30 (44.8%) | 14 (20.8%) | 12 (17.9%) |
| Males (N=27) | 22.2% | 55.6% | 11.1% | 11.1% |
| Females (N=40) | 12.5% | 37.5% | 27.5% | 22.5% |
| Adductb (+) subjects (N=47) | 19.1% | 40.4% | 23.4% | 17.02% |
| Adductb (−) subjects (N=20) | 10.0% | 55.0% | 15.0% | 20.0% |
| Smokers (N=25) | 24.0% | 64.0% | 0.0% | 12.0% |
| Nonsmokers (N=42) | 11.9% | 33.3% | 33.3% | 21.4% |
| Family history of renal disease (N=18)a | 16.7% | 27.8% | 16.7% | 38.9% |
| No family history of renal disease (N=28)a | 14.3% | 50.0% | 25.0% | 10.7% |
| Age mean (years), N=67 | 72.9 | 72.8 | 75.0 | 73.8 |
| Age range | 65–85 | 57–89 | 69–80 | 63–80 |
a
Information regarding family history of renal disease was not available for 21 subjects.
b
Adduct refers to the presence (+) or absence (−) of aristolactam-DNA adducts in renal cortex. UUC, upper urinary tract urothelial cell carcinoma