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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Future Med Chem. 2012 Jun;4(9):1093–1111. doi: 10.4155/fmc.12.58

Figure 13. DNA Ligase-1.

Figure 13

(A) Structure of the DNA-binding domain of DNA ligase-I with the predicted binding site in red and residues His-337, Arg-449 and Gly-453 that constitute the potential binding pocket. (B) Predicted docking of some of the ligase inhibitors (Figure 14) with the DNA-binding domain [112].