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. Author manuscript; available in PMC: 2013 Jan 31.
Published in final edited form as: J Neurosci Res. 2011 Feb 2;89(4):544–551. doi: 10.1002/jnr.22576

Fig. 3.

Fig. 3

Increased MCP-1 expression requires LRP1. A: Schwann cells were pretreated with GST-RAP (100 nM) or GST and then with α2M or α2M-MA for 6 hr, and MCP-1 mRNA was determined. B: LRP1 mRNA was determined by qPCR 30 hr after introducing LRP1-specific siRNA or NTC siRNA. C: LRP1 gene silencing also was assessed by immunoblot analysis using antibody 11H4. D: Schwann cells transfected with LRP1-specific or NTC siRNA were treated with native α2M or α2M-MA, and MCP-1 mRNA was determined.