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. 2013 Jan 31;9(1):e1003219. doi: 10.1371/journal.pgen.1003219

Figure 4. The Effect of Reduced Coverage on the Assignment of Regions and Variants by IBD.

Figure 4

(A) The proportion of ENU homozygous and heterozygous IBD regions from the full 24× coverage dataset identified at simulated lower depths of coverage per mouse. (B) The proportion of homozygous and heterozygous IBD variants from the 24× coverage dataset identified at simulated lower depths of coverage per mouse. The validated variants are the coding or splice variants confirmed by Sanger sequencing (Table S1). (C) The number of IBD homozygous SNPs at different simulated coverage depths compared to the number of shared homozygous SNPs across all 3 mice. (D) The number of IBD heterozygous SNPs at different simulated coverage depths compared to the number of shared heterozygous SNPs across all 3 mice.