Figure 5.

Differential transcription of genes encoding enzymes involved in the biosynthesis of CS repeating unit. (A,B) Relative transcript abundance of mRNAs for enzymes involved in the modification of CS chains. Relative abundance for healthy tissues (gray bars) and tumors (black bars) are plotted on a logarathmic scale for each gene assayed and spreads represent the standard deviations. (A) Non-metastatic IDCs. (B) Metastatic IDCs. (C) Relative expression ratio of genes that show statistically significant differences in expression in non-metastatic (●) and metastatic (■) IDCs. Values on the Y axis are represented on a logarithmic scale.