Table 1.
Baseline clinical characteristics and radiation exposure (main analysis)
| Breast cancer | Prostate cancer | |
|---|---|---|
| Patients with radiation to the bone, n |
207 |
213 |
|
Demographics |
|
|
| Mean age, years (SD) |
65 (12.5) |
74 (8.4) |
| Age, n (%) |
|
|
| <65 years |
93 (44.9) |
31 (14.6) |
| ≥65 years |
114 (55.1) |
182 (85.4) |
| Female, n (%) |
202 (97.6) |
n/a |
| Payor,* n (%) |
|
|
| Medicare |
103 (49.8) |
133 (62.4) |
| Commercial |
94 (45.4) |
64 (30.0) |
| Medicaid |
7 (3.4) |
3 (1.4) |
| Other |
3 (1.4) |
13 (6.1) |
|
Radiation profile |
|
|
| Total REOCs, n |
220 |
233 |
| Length of treatment, days |
|
|
| Mean (SD) |
30 (16.0) |
30 (16.7) |
| Median |
26 |
26 |
| Dose, cGy |
|
|
| Mean by episode |
3207 |
3301 |
| Mean per patient |
3409 |
3611 |
| Mean by fraction |
327 |
337 |
| Radiation schedule by REOC, n |
|
|
| Daily |
201 |
203 |
| Greater than daily |
7 |
13 |
| Less than daily** |
0 |
0 |
| Site radiated by REOC*** n (%) |
|
|
| Femur |
14 (6.8) |
28 (13.1) |
| Hip |
45 (21.7) |
40 (18.8) |
| Humerus |
3 (1.4) |
9 (4.2) |
| Pelvis |
20 (9.7) |
34 (16.0) |
| Rib |
12 (5.8) |
12 (5.6) |
| Sacrum |
21 (10.1) |
17 (8.0) |
| Skull |
9 (4.3) |
10 (4.7) |
| Spine |
97 (46.9) |
95 (44.6) |
| Other bone sites |
28 (13.5) |
27 (12.7) |
| Total fractions |
2173 |
2344 |
| Fractions by REOC |
|
|
| Mean (SD) |
9 (5) |
10 (4) |
| Median |
10 |
10 |
| Fractionation schedule,† n |
|
|
| 1 |
9 |
10 |
| 4 to 5 |
21 |
23 |
| 10 |
35 |
43 |
| 15 |
47 |
47 |
| Other |
102 |
96 |
| Fractions by site,‡ n |
|
|
| Femur |
10.2 |
9.7 |
| Hip |
10.0 |
9.6 |
| Humerus |
9.0 |
10.3 |
| Pelvis |
8.7 |
8.1 |
| Rib |
9.4 |
5.0 |
| Sacrum |
10.6 |
10.9 |
| Skull |
11.3 |
10.5 |
| Spine |
9.9 |
10.2 |
| Other bone site | 8.8 | 10.4 |
*A patient could have multiple payor coverage for the same procedure.
** Every other day.
*** A patient could be counted multiple times with radiation to the same site or to multiple sites.
† Fractionation schedule is the count of unique patients by the range of total number of fractions across REOCs.
‡ Fractions by site are a sum of all fractions received across REOCs stratified by bone site.