Table 1. Pairwise nucleotide and amino acid sequence identities between human enterovirus 85 strains and prototype strains of the HEV-B species.
Region | Nucleotide identity (%) [Amino acid identity (%) ] | |||||||||
HT-LYKH202F | HTYT-ARL-AFP02F | HTYT-ARLH403F | HTPS-MJH21F | HTPS-MKLH04F | ||||||
Prototype of HEV85 | Prototypes of other HEV-B | Prototype of HEV85 | Prototypes of other HEV-B | Prototype of HEV85 | Prototypes of other HEV-B | Prototype of HEV85 | Prototypes of other HEV-B | Prototype of HEV85 | Prototypes of other HEV-B | |
5′-UTR | 91.5 | 79.6–88.4 | 91.3 | 79.4–88.3 | 91.2 | 79.5–88.2 | 91.3 | 79.3–88.3 | 91.2 | 79.2–88.2 |
VP4 | 89.3 (100) | 69.0–81.1 (75.3–95.6) | 89.8 (100) | 68.5–81.1 (75.3–95.6) | 89.8 (98.5) | 68.5–81.1 (75.3–94.2) | 89.8 (100) | 69.0–81.6(75.3–95.6) | 90.3 (100) | 69.0–80.6 (75.3–95.6) |
VP2 | 89.5 (98.8) | 64.9–72.5 (75.5–83.2) | 89.2 (98.4) | 64.9–72.2 (75.5–83.2) | 89.6 (98.8) | 64.5–72.2 (75.5–83.2) | 89.1 (98.8) | 65.0–72.9 (75.5–83.5) | 89.6 (98.4) | 64.9–72.4 (75.5–83.2) |
VP3 | 90.0 (98.7) | 63.1–71.0 (66.9–81.9) | 89.9 (98.7) | 63.1–71.1 (66.9–81.9) | 88.9 (99.1) | 63.2–70.4 (66.9–81.9) | 89.3 (98.7) | 62.8–70.7 (66.9–81.5) | 89.9 (99.1) | 63.1–70.7 (66.9–81.9) |
VP1 | 89.4 (98.9) | 55.5–69.8 (57.3–75.6) | 89.4 (98.6) | 55.9–69.7 (57.3–75.2) | 89.1 (98.6) | 55.6–69.0 (57.0–75.6) | 89.0 (97.9) | 55.5–69.7 (57.0–75.2) | 89.6 (98.9) | 55.6–69.1 (57.3–75.6) |
2A | 79.3 (94.6) | 75.1–81.7 (84.6–96.0) | 79.5 (94.6) | 74.8–81.5 (84.6–96.0) | 79.7 (94.6) | 75.3–81.1 (84.6–96.0) | 80.2 (95.3) | 74.8–81.5 (85.3–96.6) | 80.0 (94.6) | 75.5–81.7 (84.6–96.0) |
2B | 80.1 (94.9) | 75.7–83.8 (93.9–98.9) | 80.4 (94.9) | 75.0–83.5 (93.9–98.9) | 80.1 (94.9) | 75.0–83.5 (93.9–98.9) | 80.8 (94.9) | 76.0–83.1 (93.9–98.9) | 79.4 (94.9) | 75.0–83.1 (93.9–98.9) |
2C | 83.8 (98.4) | 79.2–84.9 (96.3–99.0) | 84.3 (98.7) | 79.4–84.9 (96.6–99.3) | 84.1 (99.0) | 79.5–85.2 (96.9–99.6) | 84.3 (98.7) | 79.6–85.1 (96.6–99.3) | 84.0 (97.8) | 79.1–84.7 (85.7–99.0) |
3A | 80.1 (97.7) | 75.6–85.3 (91.0–98.8) | 80.5 (97.7) | 76.0–85.7 (91.0–98.8) | 80.5 (97.7) | 76.0–85.7 (91.0–98.8) | 79.4 (97.7) | 74.9–84.6 (91.0–98.8) | 80.1 (97.7) | 75.6–85.3 (91.0–98.8) |
3B | 84.8 (100) | 69.6–87.8 (90.9–100) | 87.8 (100) | 72.7–87.8 (90.9–100) | 87.8 (100) | 72.7–87.8 (90.9–100) | 86.3 (100) | 71.2–89.3 (90.9–100) | 86.3 (100) | 71.2–89.3 (90.9–100) |
3C | 83.9 (98.9) | 75.9–85.7 (92.8–99.4) | 83.7 (98.3) | 75.9–85.6 (92.3–98.9) | 83.9 (98.9) | 76.1–85.7 (92.8–99.4) | 84.3 (98.9) | 76.1–86.1 (92.8–99.4) | 84.1 (98.9) | 75.7–85.4 (92.8–99.4) |
3D | 84.9 (97.6) | 77.5–85.6 (95.0–98.2) | 85.5 (98.0) | 78.1–86.1 (95.4–98.8) | 85.4 (97.8) | 77.8–86.2 (95.2–98.4) | 85.1 (97.8) | 77.7–85.7 (95.2–98.4) | 85.6 (98.0) | 77.9–86.0 (95.4–98.7) |
3′-UTR | 87.5 | 74.0–91.3 | 87.5 | 75.0–91.3 | 88.4 | 74.0–92.3 | 87.5 | 73.0–91.3 | 88.4 | 74.0–92.3 |