Table 2. Data from offspring of the mothers fed standard chow (SC) or high-fat diet (HF).
Data | Offspring | ||
SC | HF | P-value | |
Day 0 (birth day) | |||
Male∶female ratio | 1∶1 | 1∶1 | ns |
Litter offspring number | 7±1 | 6±1 | ns |
Mean offspring mass, g | 1.30±0.03 | 1.44±0.08 | ns |
Number of dead pups per dam group, % | 3/126 | 16/102 | 0.0013 |
Three-mo-old | |||
OGTT, AUC, a.u. | 15,320.0±689.0 | 19,554.0±493.0 | 0.0011 |
Insulin, pg/mL | 102.2±11.04 | 204.8±9.93 | 0.0001 |
Data are expressed as mean and SEM. P-values of the differences between groups are indicated (unpaired t-test or Fisher exact test). Legend: OGTT = oral glucose tolerance test; AUC = area under the curve; a.u. = arbitrary units; ns = not significant.