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. 2013 Jan 31;8(1):e55286. doi: 10.1371/journal.pone.0055286

Table 1. Summary of urine data from mice receiving different treatments.

pH Volume/BW (g/g) PO4/creatinine (mM/mg/dl) NH4 +/creatinine (mM/mg/dl) Na+/creatinine (mM/mg/dl) K+/creatinine (mM/mg/dl) Cl/creatinine (mM/mg/dl)
Control 1 6.19±0.08 0.04±0.01 1.00±0.15 0.77±0.19 1.97±0.21 4.66±0.28 4.56±0.51
NH4Cl 5.48±0.02*** 0.04±0.01 0.61±0.17 6.54±0.81** 2.57±0.33 5.54±0.51 11.68±1.61**
NaHCO3+DOCA 8.48±0.15*** 0.10±0.03 0.62±0.21 0.08±0.03*** 15.28±2.01*** 3.83±0.52 3.84±0.36
NaCl 6.30±0.14 0.09±0.02 0.79±0.11 0.25±0.02** 11.34±0.89*** 3.93±0.48 17.08±2.18***
Control 2 6.28±0.08 0.04±0.01 0.93±0.14 0.42±0.02 2.23±0.16 6.30±0.44 4.44±0.39
DOCA 6.52±0.02* 0.05±0.01 1.10±0.14 0.77±0.06*** 2.88±0.22* 7.72±0.31* 5.80±0.17**
Control 3 6.34±0.07 0.09±0.01 1.41±0.13 0.42±0.03 2.71±0.34 9.34±1.11 5.17±0.65
NaHCO3 8.29±0.18*** 0.05±0.01 0.93±0.10* 0.06±0.01*** 13.12±0.47*** 6.47±0.40 3.87±0.30
Control 4 6.00±0.13 0.05±0.00 0.94±0.06 0.79±0.20 1.34±0.05 5.19±0.33 3.59±0.27
KCl 5.75±0.17 0.12±0.03* 1.36±0.12* 0.66±0.16 3.15±0.28*** 29.70±4.07*** 24.96±4.97**
KHCO3 8.11±0.09*** 0.10±0.01** 1.07±0.16 0.23±0.13* 1.97±0.34 20.21±2.48*** 4.56±0.60

All animals were treated for 7 days and placed into metabolic cages for the final 3 days. Urine analysis was performed from samples collected under mineral oil over the last 24 hrs. Values are means ± SE; n = 5–7/group. Shown is a summary of urinary data from all different treatment groups and the corresponding controls. BW, body weight, crea creatinine.

*

p<0.05,

**

p<0.01,

***

p<0.001.