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. 2013 Jan 31;8(1):e53853. doi: 10.1371/journal.pone.0053853

Table 2. Expression of proteins deemed statistically significantly (standard deviation of less than 5% of Average Log M or has an Average Log M of greater than ±0.2) differentially expressed proteins as determined by antibody array analyses in MCF-7 and MDA-MB-231 cells exposed to ESE-16 (200 nM) for 24 h.

RefSeq RNA Gene ID Protein ID Description MCF-7 MDA-MB-231
Average Log2 STDEV Average Log2 STDEV
Cell death
BAX 581 Q07814 BCL2-associated X protein 0.23 0.067
EPB49 2039 Q08495 Erythrocyte membrane protein band 4.9 (dematin) 0.77 <0.001 0.63 0.115
CASP4 837 P49662 Caspase 4, apoptosis-related cysteine protease 0.32 0.001
CASP7 840 P55210 Caspase 7, apoptosis-related cysteine protease 0.23 0.06
STAT3 6774 P40763 Signal transducer and activator of transcription 3 0.23 0.062 0.46 0.071
DAB2 1601 P98082 Disabled homolog 2, mitogen-responsive phosphoprotein 0.47 0.022
Cell cycle
CCNB1 891 P14635 Cyclin B1 0.15 0.001
BUB3 9184 O43684 BUB3 budding uninhibited by benzimidazoles 3 0.34 0.144
Protein folding
HSP60 3329 P10809 Heat shock 60 kDa protein 1 (chaperonin) 0.2 0.05
HDJ-2 3301 P31689 DnaJ (Hsp40) homolog, subfamily A, member 1 0.31 0.05 0.24 0.04
HSPA1A 3303 P08107 Heat shock 70 kda protein 1A 0.32 0.053
Ras-related
CSK 1445 P41240 c-Src tyrosine kinase 0.27 0.004 0.19 0.017
ARHGEF7 8874 Q14155 Rho guanine nucleotide exchange factor (GEF) 7 0.29 0.035 0.21 0.073
ARHGDIB 397 P52566 Rho GDP dissociation inhibitor (GDI) beta 0.24 0.008
RASA2 5922 Q15283 RAS p21 protein activator 2 0.27 0.062
RAC1 5879 P15154 Ras-related C3 botulinum toxin substrate 1 0.44 0.062
Ras-GAP 5921 P20936 RAS p21 protein activator (GTPase activating protein) 1 0.2 0.12
Transcription and translation
TCERG1 10915 O14776 Transcription elongation regulator 1 (CA150) 0.28 0.013 0.29 0.019
NASP 4678 P49321 Nuclear autoantigenic sperm protein (histone-binding) 0.27 0.013 0.58 0.025
RPS6KB1 6198 P23443 Ribosomal protein S6 kinase, 70 kda, polypeptide 1 0.12 0.011
NCOR2 9612 Q9Y618 Nuclear receptor co-repressor 2 1.11 0.127