Figure 1.

Comparison of the extent of the four deletions found in our study along with the three deletions shown in Sankaran et al.,⁶ the Sicilian (δβ)⁰ 13.4 kb deletion and the Sicilian HPFH-5 12 kb deletion. The BCL11A binding-site laying 1.5 kb 5' δ-globin gene (yellow vertical rectangle) is removed for 23.7 kb deletion as in the 49.8 kb Sri Lanka deletion⁶ and the Sicilian HPFH-5 deletion, while it is maintained for 12.6 kb, 20.7 kb Turkish deletion-inversion, Sri Lanka (δβ)⁰ and Sicilian (δβ)⁰ deletions.