Standard dosage | 10–50 mg/kg/d divided into two doses. |
Contraindications | DCA induces dose-dependent and exposure-dependent reversible peripheral neuropathy. Patients with certain mitochondrial disorders (eg, MELAS) are probably more prone than others to the toxic effects of DCA. |
Main drug interactions | None known. |
Main side effects | DCA may induce mild elevation of liver transaminase. |