Table 2b.

Infliximab trough levels (μg/ml) in IBD patients who had loss of response vs. no loss of response (median and IQR range, unless otherwise stated)

Study	N	Lost response	Maintained remission	P value
Ainsworth et al. (16)	27	0 (0–0.1)	2.9 (0.9–4.3)	0.002
Yamada et al.a (50)	31	6.3	4.7	NS
Steenholdt et al. (22)	69	0 (0–0)	2.8 (0.8–5.3)	< 0.0001
Pariente et al.b (20)	76	3.3 (±4.1)	2.3 (±2.2)	NS
Steenholdt et al.c (22)	13	0 (0–0)	3.8 (1.1–8.5)	< 0.0001
Arias et al.c (59)	136	0.3 (0.3–3.6)	4.9 (1.7–8.2)	0.01

IBD, inflammatory bowel disease; IQR, interquartile range.

^aNo IQR given.

^bData are represented as mean values (±s.d.).

^cIndicates patients with ulcerative colitis.