Figure 1.
Top panel: Normalized mean antibody titer concentrations (µg/ml) for MH2(R), MH6, and MH7 across 12 weeks. Arrows depict vaccinations (weeks 0, 2, 5, and 9). Acute METH challenges are shown by the box labeled ‘METH.’ Bottom panel: Mean antibody titer (dilution) across 12 (Experiment 1) and 20 weeks (Experiment 2) for MH6-vaccinated rats (N=8 per group). Acute METH challenges for Experiments 1 and 2 are shown by the boxes labeled ‘METH’ or ‘M’ in the top and bottom row, respectively; surgery is depicted by “s” for rats in Experiment 2. Error bars are ±SEM.