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Mean body temperature values (°C; top panel) and locomotor activity (bottom panel) across successive 30-min intervals following challenge doses of METH (0.0, 0.5, 1.0, 3.2, 5.6 mg/kg) in MH6-vaccinated and KLH-control rats at TA = 23°C (Experiment 2). Significant differences between and within groups are shown by * and #, respectively. Note that the y-axis values differ for locomotor activity at the 5.6 mg/kg dose. Error bars are ±SEM.
