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. Author manuscript; available in PMC: 2013 Aug 1.

Published in final edited form as: Kidney Int. 2012 Dec 12;83(2):242–250. doi: 10.1038/ki.2012.391

Representative renal histology of SS, BN and selected consomic rat strains 24 hours following I/R injury. Photomicrographs are shown in the renal outer medulla for the BN (A), SS (B), SS-1^BN (C), SS-4^BN (D), SS-7^BN (E) and SS-8^BN (F). White arrows indicate PAS-positive brush border staining, while area of necrotic cellular debris are indicated by *. In some tubules, although cellular debris is present, dedifferentiated and viable cells are clearly seen (thick arrow). Panel G is quantitative analysis of tubular injury scores for renal cortex (open) or outer medulla (hashed bar). Data are expressed as percent affected tubules and are mean ± SE. The N for each group is shown; * P < 0.05 indicates significantly reduced vs SS rats; # indicates injury in BN is less than the consomic protected strains.

Representative renal histology of SS, BN and selected consomic rat strains 24 hours following I/R injury. Photomicrographs are shown in the renal outer medulla for the BN (A), SS (B), SS-1^BN (C), SS-4^BN (D), SS-7^BN (E) and SS-8^BN (F). White arrows indicate PAS-positive brush border staining, while area of necrotic cellular debris are indicated by *. In some tubules, although cellular debris is present, dedifferentiated and viable cells are clearly seen (thick arrow). Panel G is quantitative analysis of tubular injury scores for renal cortex (open) or outer medulla (hashed bar). Data are expressed as percent affected tubules and are mean ± SE. The N for each group is shown; * P < 0.05 indicates significantly reduced vs SS rats; # indicates injury in BN is less than the consomic protected strains.