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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Kidney Int. 2012 Dec 12;83(2):242–250. doi: 10.1038/ki.2012.391

Figure 3.

Figure 3

In silico analysis to identify potential candidate genes that confer protection in AKI. To generate a list of potential candidate genes that play a role in the resistance to ischemic injury found in the BN strain, an in silico analysis was done to identify candidate genes involved in the resistance to I/R induced AKI. A: Number of genes with annotations to three disease ontology (DO) terms (reperfusion injury, ischemia, kidney disease) for the resistant chromosomes (consomics with a resistant phenotype). B: Number of renal function quantitative trait loci (QTL) located on chromosomes that protect against I/R injury. C: Potential candidate genes were identified if gene has DO annotations for reperfusion injury, ischemia, and kidney disease and were found within a renal function QTL. D: Summary of candidate genes and the QTLs that overlap with the candidate genes.