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. Author manuscript; available in PMC: 2013 Jul 31.
Published in final edited form as: Nature. 2012 Oct 24;493(7434):627–631. doi: 10.1038/nature11647

Figure 2. Abnormal pronuclear formation and spindle morphology in human ST zygotes.

Figure 2

a, Proportion of normally fertilized zygotes with 2 pronuclei and 2 polar bodies (2PN/2PB) vs. abnormal zygotes (3PN/1PB; 3PN/2PB; 1PN; multiple PN and 2-cell) after ST. b, Integrity of meiotic spindles in human ST oocytes depicting normal metaphase II (top), and premature progression to the anaphase II (bottom).