Table 1.
Test | Density (mice/pen) | Density group
|
Sex
|
|||
---|---|---|---|---|---|---|
Mean ± SEM | P value | Mean ± SEM
|
P value | |||
Females | Males | |||||
Bone mineral density (g/cm2)*1 | 5 | 0.0469 ± 0.0003 | ns | 0.0460 ± 0.0003 | 0.0477 ± 0.0003 | 0.0002 |
9 | 0.0476 ± 0.0004 | 0.0466 ± 0.0005 | 0.0484 ± 0.0004 | |||
% Body fat*1 | 5 | 20.9 ± 1.3 | ns | 23.8 ± 1.6 | 17.9 ± 0.6 | 0.001 |
9 | 21.4 ± 0.6 | 22.6 ± 1.0 | 20.4 ± 0.4 | |||
Food consumption (g/wk)2 | 5 | 18.5 ± 0.2 | 0.02 | 20.2 ± 0.2 | 16.9 ± 0.2 | <0.0001 |
9 | 17.5 ± 0.2 | 19.2 ± 0.2 | 15.8 ± 0.1 | |||
Water consumption (g/wk)2 | 5 | 17.8 ± 0.2 | 0.053 | 19.8 ± 0.2 | 16.0 ± 0.2 | <0.0001 |
9 | 17.5 ± 0.2 | 19.6 ± 0.3 | 15.3 ± 0.2 | |||
Adrenal weight (mg)*3 | 5 | 6.8 ± 0.4 | 0.001 | 7.6 ± 0.4 | 6.0 ± 0.5 | <0.0001 |
9 | 5.4 ± 0.4 | 6.4 ± 0.3 | 4.4 ± 0.2 |
The difference between sexes reached statistical significance at P < 0.05; however, the interaction between sex and density did not.
Transformations applied:sqrt.
Food and water consumption are normalized to a 25-gram mouse.
For adrenal weight, body weight was not found to be a significant covariate (P < 0.05).