Table 3.
No./Total No. (%)
|
P Value | |||
---|---|---|---|---|
NMO | MS | |||
Pain medications | 22/29 (75.9) | 25/66 (37.8) | <.001 | |
≥2 Pain medications | 19/29 (65.5) | 10/66 (15.2) | <.001 | |
Neuropathic medicationsa | 17/29 (58.6) | 16/66 (24.2) | .005 | |
Antiepileptic (sodium-channel blocking) medicationsb | 19/29 (65.5) | 6/66 (9.1) | <.001 | |
Antispasticity medicationsc | 11/29 (37.9) | 12/66 (18.2) | .03 | |
Opioidsd | 9/29 (31.0) | 8/66 (12.1) | .006 | |
Current pain level while taking pain medication | ||||
Pain free (0) | 0/22 (0) | 12/25 (48.0) | .001 | |
Mild pain (1–3) | 2/22 (9.1) | 4/25 (16.0) | ||
Moderate pain (4–7) | 7/22 (31.8) | 4/25 (16.0) | ||
Severe pain (8–10) | 13/22 (59.1) | 5/25 (20.0) |
Abbreviations: MS, multiple sclerosis; NMO, neuromyelitis optica.
Neuropathic: tricyclic antidepressants, gabapentin, pregabalin, and duloxetine hydrochloride.
Antiepileptic: phenytoin, carbamazepine, sodium valproate, and lamotrigine.
Antispastic: baclofen, tizanidine hydrochloride, and cyclobenzaprine hydrochloride.
Opioids: hydrocodone, methadone hydrochloride, oxycodone, hydromorphone, and fentanyl citrate.