Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Dec 20;288(5):3025–3035. doi: 10.1074/jbc.M112.424770

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

FIGURE 4. — Modulation of Pak1 activity in androgen-responsive and androgen-insensitive prostate cancer cells inhibits directional migration of prostate cancer cells. a–c, human androgen-responsive LNCaP and androgen-insensitive PC3 and LNCaP C4-2 cells were either overexpressed with CA-Pak1 or DN-Pak1 (in the case of PC3 and LNCaP), or made stable cell lines expressing ShPak1 (in the case of LNCaP C4-2) and then subjected to a migration assay on fibronectin in the presence of 50 μm EGF. The data are presented as mean ± S.D. n = 3 of quadruplicate experiments. *, p < 0.001; #, p < 0.05; Δ, p < 0.01; versus control experiments within the same group.