TABLE 1.

Junctional coupling for Cx32WT, mutants, and controls expressed in N2a cells in the homotypic and heterotypic configuration

Pairing	n	Mean (ps)	S.D.	S.E.	p vs. WT	P vs. ie
32WT/32WT	7	41,900	41,900	13,100		***
R75P/R75P	7	7.71	2.40	7.71	***	ns
R75Q/R75Q	7	22.1	43.6	16.5	**	ns
R75W/R75W	9	10.4	21.7	7.24	***	ns
R75D/R75D	7	35.3	74.7	28.2	**	ns
R75E/R75E	5	49.2	58.8	19.3	**	ns
R75H/R75H	31	827	2930	526	***	ns
R75K/R75K	14	6720	10,600	2840	ns	**
R75A/R75A	22	2750	9950	2120	***	ns
R75L/R75L	9	13,700	18,900	6310	ns	**
R75V/R75V	15	18.3	48.6	12.5	***	ns
E47R*R75E/E47R*R75E	8	16.3	30.2	11.7	***	ns
R75E*E186R/R75E*E186R	17	172	275	72.5	**	ns
32WTie/32WTir	15	20,600	21,800	5830		***
R75Pie/32WTir	16	29.4	63.3	15.8	***	ns
R75Qie/32WTir	11	205	222	67.2	*	ns
R75Wie/32WTir	11	53.6	81.3	24.5	***	ns
R75Die/32WTir	10	62.0	140	44.5	***	ns
R75Eie/32WTir	7	27	37.63	14.22	**	ns
R75Hie/32WTir	28	11,900	19,100	3620	ns	***
R75Kie/32WTir	19	12,400	19,200	4400	ns	***
R75Aie/32WTir	6	0	0	0	***	ns
R75Lie/32WTir	12	5280	7280	2100	ns	**
R75Vie/32WTir	6	0	0	0	***	ns
E47R*R75E/32WTir	7	0	0	0	***	ns
R75E*E186R/32WTir	5	56	125	56	**	ns
ie (empty vector)	10	0	0	0	***

Homotypic expressing cells were all transfected using pIRES2-EGFP vectors. ie indicates pIRES2-EGFP; ir indicates pIRES2-dsRed; ns indicates not significant.

*, p < 0.05;

**, p < 0.01;

***, p < 0.001.