Table 3. Liver UPR Transcripts Significantly Altered T/HS vs. Sham, T/HS/IL6 vs. T/HS and T/HS/IL6/GQ Comparisons.
Regulation | Fold Change | |||||
---|---|---|---|---|---|---|
Gene Symbol | T/HS vs Sham | T/HS-IL6 vs T/HS | T/HS-IL6-GQ vs T/HS-IL6 | T/HS vs Sham | T/HS-IL6 vs T/HS | T/HS-IL6-GQ vs T/HS-IL6 |
Hspa1a/Hspa1b (Hsp70) | up | up | down | 25.6 | 5.5 | −9.0 |
Hspa1b (Hsp701b) | up | up | down | 18.4 | 5.9 | −10.8 |
Ero1l | up | down | down | 9.8 | −3.8 | −1.3 |
Dnajb1 (Hsp40 subunit) | up | up | down | 5.9 | 2.7 | −3.4 |
Casp3 (Caspase 3) | up | down | up | 1.8 | −1.7 | 1.4 |
Sels | up | down | up | 1.5 | −1.3 | 1.4 |
Eif2ak3 (PERK) | up | down | down | 1.4 | −1.3 | −1.3 |
Psmb3 | down | up | up | −1.2 | 1.3 | 1.9 |
Uba1 | down | up | up | −1.3 | 1.2 | 1.8 |
Psme2 | down | up | up | −1.3 | 1.4 | 2.9 |
Psme1 | down | up | up | −1.3 | 1.2 | 2.2 |
Tmbim6 (Bax inhibitor 1) | down | up | down | −1.5 | 1.3 | −1.2 |