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Increase of plasma cells and increased numbers of white pulp in the Il6rahIL6R/hIL6R-hIL6 transgenic mouse (b, e) were ameliorated after 4-week treatment with tocilizumab (c, f). Plasma cells are shown in insert (b). Bars: (a–c), 100 μm; (d–f), 500 μm. W, white pulp.
