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. 2012 Oct 5;112(2):132–137. doi: 10.1111/j.1742-7843.2012.00932.x

Table 1.

Multiple reactions monitoring parameters for the detection of prasugrel, prasugrel active metabolite, prasugrel active metabolite-d3, midazolam, omeprazole, bupropion and flurbiprofen

Compounds Polarity Q1→Q3 (m/z) CE (V) DP (V) Dwell time (ms) LLQ (ng/ml)
Prasugrel + 374→206 23 100 2 0.5
Prasugrel AM1 + 498→348 28 100 2 0.5
Prasugrel AM-d31 + 501→348 25 150 2 0.5
Midazolam + 326→291 37 165 2 0.1
Omeprazole + 346→198 19 66 2 0.5
Bupropion + 240→131 30 80 2 0.5
Flurbiprofen + 243→199 18 50 2 100

CE, collision energy; DP, declustering potential; LLQ, lower limit of quantification.

1

Compounds derivatized with 2-bromo-3-methoxyacetophenone (BMAP).