Table III.
Influence of Geographical Region and Other Covariates on Survival of Children With Cancer Covered by the Fund for Protection Against Catastrophic Expenditures
| All types of cancer | Leukemia | CNS tumors | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hazard ratio | 95% CI | Hazard ratio | 95% CI | Hazard ratio | 95% CI | ||||||||||
| Geographical region | |||||||||||||||
| West | 1.4 | 1.1–1.7 | 1.4 | 1.1–1.8 | 1.1 | 0.5–2.5 | |||||||||
| Northwest | 1.8 | 1.4–2.4 | 1.5 | 1.0–2.3 | 2.5 | 1.3–5.0 | |||||||||
| East | 3.0 | 2.3–3.9 | 2.7 | 1.8–4.1 | 2.6 | 1.0–6.2 | |||||||||
| South-southeast | 2.4 | 2.0–2.8 | 2.6 | 2.0–3.2 | 2.2 | 1.2–4.1 | |||||||||
| Age of diagnosis | |||||||||||||||
| <1 year | 1.7 | 1.2–2.2 | 2.2 | 1.5–3.2 | 1.1 | 0.3–3.3 | |||||||||
| 5–9 years | 1.1 | 0.9–1.3 | 1.2 | 0.9–1.6 | 0.9 | 0.5–1.6 | |||||||||
| 10–14 years | 1.2 | 0.9–1.5 | 1.4 | 1.1–1.8 | 0.6 | 0.3–1.3 | |||||||||
| 15–19 years | 1.5 | 1.2–1.9 | 1.8 | 1.3–2.6 | 1.9 | 0.6–6.2 | |||||||||
| Mother schooling | |||||||||||||||
| Illiterate | 1.7 | 1.1–2.6 | 1.8 | 1.0–3.2 | 1.5 | 0.4–4.5 | |||||||||
| Primary school | 1.3 | 0.9–1.9 | 1.4 | 0.8–2.4 | 1.4 | 0.5–3.6 | |||||||||
| Secondary school | 1.2 | 0.8–1.8 | 1.3 | 0.7–2.3 | 1.2 | 0.4–3.2 | |||||||||
| Preparatory school | 1.1 | 0.8–1.7 | 1.3 | 0.7–2.4 | 1.2 | 0.4–3.8 | |||||||||
| High risk | 1.3 | 1.2–1.6 | 1.4 | 1.1–1.8 | 0.9 | 0.4–1.4 | |||||||||
| Treatment relapse | 1.2 | 1.0–1.4 | 1.3 | 1.0–1.7 | 1.1 | 0.5–2.2 | |||||||||
| Adverse events | |||||||||||||||
| Grades 2–3 | 1.4 | 1.2–1.7 | 1.4 | 1.1–1.8 | 0.9 | 0.6–1.5 | |||||||||
| Grades 4–5 | 4.9 | 4.1–5.9 | 5.1 | 4.0–6.5 | 2.3 | 0.9–5.9 | |||||||||
| Female sex | 0.9 | 0.8–1.0 | 0.9 | 0.7–1.0 | 1.3 | 0.8–2.1 | |||||||||
| Type of cancer | |||||||||||||||
| Leukemia | 1.1 | 0.8–1.4 | |||||||||||||
| CNS tumors | 2.0 | 1.4–2.7 | |||||||||||||
| Retinoblastoma | 1.4 | 0.9–2.3 | |||||||||||||
| Renal tumors | 1.3 | 0.8–2.0 | |||||||||||||
| Malignant bone tumors | 1.8 | 1.3–2.5 | |||||||||||||
| Others | 1.3 | 0.9–1.7 | |||||||||||||
Bold values indicate statistically significant results (P < 0.05) in the Cox proportional hazards model.