Table 1. Characterization of Peptide Coupling to Liposomes.
| liposome maleimide percentage |
peptide | nmole peptide/μmole phospholipid |
peptides/ liposomea |
|---|---|---|---|
| 0.64 | H2009.1 tetramer | 9.1 | 720 |
| scH2009.1 tetramer | 9.4 | 760 | |
|
| |||
| 1.3 | H2009.1 monomer | 15 | 1200 |
| H2009.1 tetramer | 18 | 1400 | |
| scH2009.1 tetramer | 19 | 1500 | |
|
| |||
| 2.0 | H2009.1 monomer | 30 | 2400 |
| H2009.1 tetramer | 30 | 2400 | |
| scH2009.1 tetramer | 32 | 2600 | |
a
Peptide number/liposome was calculated by assuming 80,000 phospholipid molecules/liposome for a liposome size of 100nm (reference 26).