Table 2.

IC₅₀ Values of Different Liposome Formulations on α_vβ₆-Positive H2009 Cells^a

Drug Formulation	IC50 on H2009 cells (nM)
0.6% H2009.1 Tetrameric	1500 ± 200
0.6% scH2009.1 Tetrameric	2400 ± 120
0.6% Naked	7400 ± 1400
1.3% H2009.1 Monomeric	5700 ± 120
1.3% H2009.1 Tetrameric	970 ± 130
1.3% scH2009.1 Tetrameric	2000 ± 330
1.3% Naked	Not reachedb
2.0% H2009.1 Tetrameric	360 ± 35
2.0% scH2009.1 Tetrameric	610 ± 90
2.0% Naked	6900 ± 960
Free Doxorubicin	430 ± 75

^aCells were incubated with liposomes for 1 hour followed by a 120 hour recovery in media.

^bNot reached at the highest treatment concentration of 10.2 μM.