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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: J Mol Endocrinol. 2012 Dec 31;50(1):10.1530/JME-12-0201. doi: 10.1530/JME-12-0201

Fig. 1. Schematic representation of the human prolactin receptor variants.

Fig. 1

(A) Major human prolactin receptor isoforms generated by alternate splicing. Pink = extracellular domain; blue = transmembrane domain; green = intracellular domain; E = exon; B I = proline-rich JAK2 docking site, B II= hydrophobic region; TGA/TAG = stop codon. (B) Illustration of the major human prolactin receptor variants. LF = long form; SF1a = short form 1a; SF1b = short form 1b, PrlBP = prolactin binding protein; TM = transmembrane domain; D1 and D2 = N terminal subdomain; AA = amino acid number including signal peptide. Adapted from Trott, et al. 2003.