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. 2013 Jan 2;123(2):700–711. doi: 10.1172/JCI62236

Figure 2. The risk for colitis in RIP2-deficient mice is maternally transmissible.

Figure 2

WT animals were reared with either a RIP2-deficient or -sufficient mother since birth (n = 4). Five-week-old cross-fostered mice were then exposed to 1 cycle of DSS-AOM, as described earlier. Changes in (A) body weight and (B) colon length were evaluated daily. (C) Representative H&E and PAS staining of paraffin-embedded transversal sections from colons of CF-WT and CF-RIP2–/– mice at day 9. CF refers to cross-fostered animals. Scale bar: 100 μm. *P < 0.05; ***P < 0.001.