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To assess the therapeutic effect of MSC–PEDF for intracranical U87MG glioma, mice were intravenously injected with MSC–PEDF 7 days after intracranial implantation of tumour cells, and intravenous injection of MSC or PBS as control groups. Intravenous injection of MSC–PEDF has more benefits on the survival of tumour-bearing mice than PBS and MSC–LacZ-treated groups (P<0.01).
