Table 2.
Main effects of late-life depression on gray matter volumes
| Brain region | Side | BA | Cluster Size (mm3) | MNI coordinates (LPI)
|
z Score | ||
|---|---|---|---|---|---|---|---|
| x | y | z | |||||
| Insula | L | 13 | 6432 | −35 | 15 | 0 | −3.24 |
| dACC | L/R | 24/32 | 4680 | −2 | 36 | 16 | −3.94 |
| pMTG/MOG | L | 19 | 3496 | −48 | −76 | 2 | −3.96 |
| IFG | L | 47 | 1840 | −45 | 30 | −16 | −3.49 |
| OFC | L/R | 25 | 1688 | 2 | 26 | −18 | −3.28 |
| PCC/Pcu | R | 31 | 1584 | 16 | −42 | 40 | −3.84 |
| vmPFC | L/R | 11 | 4 | 58 | −16 | −3.53 | |
Notes: x,y,z, coordinates of primary peak locations in the MNI space. Abbreviation: MNI, Montreal Neurological Institute space; LPI, left-posterior-inferior; BA, Brodmann’s area; R, right. L, left; dACC, dorsal anterior cingulate cortex; pMTG, posterior middle temporal gyrus; MOG, middle occipital gyrus; IFG, inferior frontal gyrus; OFC, orbitofrontal cortex; PCC, posterior cingulate cortex; Pcu, precuneus; vmPFC, ventromedial prefrontal cortex.