Table 3.
Main effects of cognitive impairment on gray matter volumes
| Brain region | Side | BA | Cluster Size (mm3) | MNI coordinates (LPI)
|
z Score | ||
|---|---|---|---|---|---|---|---|
| x | y | z | |||||
| Amy/Hippo | L/R | 34 | 52380 | 26 | 2 | −22 | −5.17 |
| vmPFC | L/R | 32/11 | 2 | 37 | −10 | −3.06 | |
| VlPFC | L/R | 11 | −24 | 55 | −16 | −4.08 | |
| Insula | L/R | 13 | −34 | 11 | −15 | −3.82 | |
| PCC/Pcu | R | 7 | 8536 | 6 | −64 | 56 | −3.83 |
| pMTG | R | 39 | 4072 | −54 | −68 | 26 | −4.35 |
| RSC | R | 31 | 2312 | 24 | −46 | 4 | −2.99 |
| FFA | L | 20 | 1728 | −40 | −25 | −29 | −3.41 |
| aTP | L/R | 20 | 1336 | −46 | −3 | −33 | −3.71 |
Notes: x,y,z, coordinates of primary peak locations in the MNI space. Abbreviation: MNI, Montreal Neurological Institute space; LPI, left-posterior-inferior; BA, Brodmann’s area; R, right. L, left; Amy/Hippo, amygdala/hippocampus; vmPFC, ventromedial prefrontal cortex; vlPFC, ventrolateral prefrontal cortex; PCC, posterior cingulate cortex; Pcu, precuneus; RSC, retrosplenial cortex; FFA, fusiform area; aTP, anterior temporal pole.