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. 2012 Dec 15;41(3):1901–1913. doi: 10.1093/nar/gks1254

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© The Author(s) 2012. Published by Oxford University Press.

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Figure 3. — Frameshift efficiency is plotted as a function of RNA stability. Data represent an average of at least three replicates, with the SEM indicated. (A) In vitro frameshift assay results for WT and MS1-12 RNAs. Error bars representing the SEM are shown. The dashed line is indicative of the WT mean. (B) Overall thermodynamic stability (at 1 M NaCl) versus frameshift efficiency. (C) Local stability (at 1 M NaCl) of first 3 bp versus frameshift efficiency. A single exponential decay function was fit to the data [y = 18(±2)e^{−0.9(±0.3)(}^X^{+ 9.8)} + 3(±1), R² = 0.88].