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Multiplexed, single-tube DISSECT. Sanger sequencing analysis from a combined bead capture experiment showing simultaneous mutation enrichment for four independent regions, KRAS exon 2 and TP53 exons 5, 6 and 8 following three rounds of DISSECT, from an original mutation abundance of 1 and 5% (mixture of SW480, SNU-182 and NCI-H69 mutant DNA diluted into wild-type DNA, MP3). Data are representative of at least three independent experiments.
