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NER or DDB2 are not required for UV-induced p300 degradation. (A–C) NER-deficient XP-A (A), XP-D (B) and XP-F (C) cells were irradiated with either UV or IR. The p300 protein level was detected at various post-exposure times. (D and E) DDB2-deficient XP-E cells (D) and p53-deficient MDAH041 cells (E) were UV irradiated and further cultured for various time. The p300 protein level was detected using western blotting.
