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. 2012 Dec 24;41(3):1848–1858. doi: 10.1093/nar/gks1276

Figure 4.

Figure 4.

R283K pol β ternary complex with a templating anti-8-oxoG:dCMP(CF2)PP base pair. (A) R283K pol β ternary complex active site with 8-oxoG in the anti-conformation base pairing with dCMP(CF2)PP. The key hydrogen bonding interactions are shown as black dashes. Mn2+ and water molecules are shown as red and blue spheres, respectively. The key active site residues and Lys283 (K283) are shown in stick format. (B) Structural overlay of the wild-type and R283K pol β ternary complexes are shown in salmon and cyan, respectively. Mn2+ from the R283K pol β structure is shown as red spheres and the Mg2+ from the wild-type pol β structure is shown in green.