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HopA1-ShcA interactions. (A) Hydrophobic patches in ShcA (yellow) that bind the HopA1 polypeptide (shown as a ribbon cartoon in salmon); (B) residues making contact between the S2 strand (β-motif) of HopA1 (salmon and orange) and ShcA (purple and blue); (C) contacts between the HopA1 H2 helix and the ShcA helix-binding groove.
