Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
LcrVS324 causes a dominant negative LCR− phenotype in Y. pestis harboring calcium-blind alleles yscFD28A and/or yscFD46A. (A) Y. pestis YP517 (ΔyopE/sycE) harboring wild-type yscF, the calcium-blind alleles yscFD28A and/or yscFD46A, or the LCR− yscFD77A allele were transformed with plcrVS324. Strains without (top panels) or with plcrVS324 (bottom panels) were cultured at 37°C in TMH medium supplemented with either 0 mM or 6.25 mM CaCl2. Growth was recorded as an increase in the OD600.
