Table 3.
Median biomarker levels [25-75% IQR], (range) when AKI is defined as a >50% increase in serum creatinine
| AKI | no AKI | p-value | |
|---|---|---|---|
|
Urine IL-18 (pg/mL) |
|
|
|
| pre-op |
0 |
0 |
0.4274 |
| [0–18.57] |
[0–0] |
||
| (0–1369) |
(0–32.16) |
||
| post-op |
884.09 |
0 |
0.0449 |
| [0–5024.4] |
[0–42.73] |
||
| |
(0–5024.4) |
(0–4915.6) |
|
|
Urine NGAL (ng/mL) |
|
|
|
| pre-op |
20.27 |
6.52 |
0.1848 |
| [4.70-272.12] |
[3.41-10.76] |
||
| (0.97-8672.2) |
(0.05-56.82) |
||
| post-op |
386.86 |
24.31 |
0.0039 |
| [71.38-1611.48] |
[9.97-45.20] |
||
| (41.23-1824.6) |
(1.69-5522.1) |
||
|
Urine IL-6 (pg/mL) |
|
|
|
| pre-op |
6.82 |
6.34 |
0.1577 |
| [4.28-50.11] |
[1.59-9.36] |
||
| (1.90-376.58) |
(0–40.59) |
||
| post-op |
52.00 |
7.29 |
0.0532 |
| [5.55-77.22] |
[3.81-13.16] |
||
| (20.61-84.04) |
(0.48-130.34) |
||
|
Serum IL-6 (pg/mL) |
|
|
|
| pre-op |
14.21 |
10.28 |
0.6693 |
| [5.75-24.19] |
[6.05-17.54] |
||
| (3.33-67.14) |
(1.21-60.18) |
||
| post-op |
44.76 |
18.75 |
0.1025 |
| [17.54-133.67] |
[9.38-38.71] |
||
| (13–3020.6) |
(4.23-171.77) |
||
|
Urine IL-8 (pg/mL) |
|
|
|
| pre-op |
0 |
0 |
0.1881 |
| [0–131.70] |
[0–0] |
||
| (0–200.1) |
(0–143.2) |
||
| post-op |
14.30 |
0 |
0.0224 |
| [0–143.00] |
[0–0] |
||
| (0–163.8) |
(0–238.8) |
||
|
Serum IL-8 (pg/mL) |
|
|
|
| pre-op |
12.36 |
6.53 |
0.6175 |
| [3.50-30.51] |
[0–36.35] |
||
| (0–114.78) |
(0–786.23) |
||
| post-op | 242.48 |
82.37 |
0.0463 |
| [97.28-341.00] |
[20.14-133.58] |
||
| (41.53-1267.5) | (0–598.99) |