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. 2013 Jan 10;7:14. doi: 10.1186/1752-1947-7-14

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Copyright ©2013 Golombeck et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Neuropathological analysis revealing laminar necrosis and hypoxic neuronal cell death in the absence of overt arterial pathology. (A,B) Gross appearance revealed cortical discoloration due to laminar necrosis (→) and small white matter hemorrhage (►) in occipitotemporal regions. (C) Histopathological analysis showed hypoxic neuronal damage (arrows) (that is, nerve cells with eosinophilic and shrunken cytoplasm and hyperchromatic condensed nucleus (hematoxylin and eosin stain ×100)) (D,E) but no evidence of any arterial vascular pathology except for minor arteriosclerosis of intracerebral (D) and basal vessels (E) (elastica-van Gieson stain ×100).