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Statistical tests
| Treatment | NDFsa | WSa | NDFs / WSb |
|---|---|---|---|
| MK2.III (5μM) |
p > 0.37 |
p < 0.05 |
p < 0.029 |
| SB203580 (2.5μM) | p < 0.05 | p < 0.036 | p < 0.014 |
a Probability that inhibitor treatment results in no significant extension of replicative capacity for NDFs or WS fibroblasts compared to DMSO-treated cells (paired t-test).
b Probability that the extension of replicative capacity seen for WS cells is not greater than that seen for NDFs for same treatment (unpaired 2-tailed t-test).
