Table 1. Effect of treatment of rats with gum arabic (GA, 15% w/v in drinking water), with or without adenine in feed (0.75% w/w) for 28 days on histopathological parameters.

Group	GSI	MSI	Fibrosis	Inflammation
Control	0.46±0.10	0.35±0.07	0.19±0.02	0.06±0.01
GA	0.49±0.13###	0.41±0.10###	0.21±0.03###	0.05±0.01###
Adenine	1.85±0.40***	1.46±0.10***	2.12±0.10***	2.70±0.18***
Adenine+GA	1.00±0.10**,###	0.77±0.10*,###	0.39±0.03###	1.29±0.10***,###

The values represent the mean ± SEM (n  = 6). * p<0.05, ** p<0.01, *** p<0.001 vs. control, ^### p<0.001 vs. control vs. adenine treatment. GSI = glomerular sclerosis index, MSI = mesangiolysis index.