Table 2. Effect of treatment of rats with gum arabic (GA, 15% w/v in drinking water), with or without adenine in feed (0.75% w/w) for 28 days on indices of oxidative stress in renal cortex and plasma.
| Group | GSH (µg/g) | SOD (U/g) | TAOAa(µg/l) |
| Control | 7.21±0.45 | 1.36±0.13 | 0.61±0.09 |
| GA | 8.01±0.85# | 1.86±0.19# | 0.75±0.11# |
| Adenine | 4.73±0.40* | 0.89±0.10* | 0.46±0.08* |
| Adenine+GA | 6.01±0.46# | 1.17±0.14# | 0.54±0.07# |
The values represent the mean ± SEM (n = 6). * p<0.05 vs. control, # p<0.05 vs. adenine treatment.
Reduced glutathione (GSH) concentration and superoxide dismutase (SOD) activity were measured in renal homogenates, and total antioxidant activity (TAOA) was estimated in plasma.
a
mM uric acid equivalents.