Table 1.

Cases of Ophthalmoplegic Migraine From Our Centers

	Case 1	Case 2	Case 3	Case 4
Age at onset (y)	5	4	9	3
Age at most recent episode (y)	19	13	16	10
Sex	M	M	F	M
Cranial nerve involved	3	3	3	3
Side	Left	Right	Right	Left
Headache location	Periorbital	Diffuse	Right frontal	Periorbital
Headache quality	Sharp, throbbing	Throbbing	Throbbing	Sharp, constant
Interval between headache onset and ophthalmoplegia	Several hours	2–3 d	Hours (overnight)	2 d
Headache duration	~8 h	2–3 d	Hours to several days	2 d
Ophthalmoplegia duration	3–7 d	–	3–7 d	Several weeks
Associated symptoms
Photophobia	Yes	Yes	No	No
Phonophobia	No	Yes	No	No
Nausea	Yes	Yes	No	Yes
Vomiting	–	Yes	–	Yes
History of other headaches	Yes	–	–	No
Family history of headache	Yes	Yes	Yes	No
Cerebrospinal fluid examination	–	–	–	Unremarkable
Vascular imaging	–	Normal MRA	–	Normal MRA
Improved with steroids	–	Yes	–	Yes
Persistent neurologic findings	No	No	No	Yes, partial third nerve palsy
MRI findings	Acute MRI showed enhancement of the cisternal portion of the third nerve Repeat MRI 1 y later was normal	Nonacute MRI was normal	Nonacute MRI was normal (no gadolinium given)	Acute MRI showed thickening and enhancement of cisternal portion of third nerve Repeat nonacute MRI showed persistent thickening but no enhancement

Abbreviations: F, female; M, male; MRA, magnetic resonance angiography; MRI, magnetic resonance imaging.