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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Neuropharmacology. 2012 Nov 16;67C:233–242. doi: 10.1016/j.neuropharm.2012.11.008

Figure 5.

Figure 5

Effects of intrahippocampally-administered nicotinic antagonists on working memory assessed in a spontaneous alternation task. (A) MLA doses of 6.75 and 13.5, but not 27 μg/side, significantly impaired alternation scores. (*) ps < .05 vs. aCSF. N = 9. (B) DHβE doses of 8 and 20, but not 4 μg/side, significantly impaired alternation scores. (*) ps < .05 vs. aCSF. N = 9. To the right of each graph is an illustration of the infusion sites targeting the dorsal hippocampus for each experiment. Filled circles represent tips of infusion tracts. Numbers refer to distance in mm posterior to bregma. Adapted with permission from Paxinos and Watson (2003).